Dad: Hey Johnny, it's almost . Your guests should be arriving soon.
Johnny: Dad, I'm not popular. I bet no one will come. I invited everyone in my class to the party, but I bet we'll be here alone.
Dad: Well son, I think you're a great kid and it was nice that you invited everyone. Let the chips fall where they may. If only a couple of people come, great. If everyone comes, great! We will have a good time either way. There's no sense in worrying about what you cannot control.
Stan placed a $200 bet on the last game of poker. He didn't know if he could win or not. His whole attitude was to let the chips fall where they may while he was staying in Las Vegas.
Imagine throwing up a handful of small plastic chips. There is no way to control where they will fall. The expression let the chips fall where they may is a way of looking at and dealing with life that accepts its randomness without too much worry. It can also be used when one isn't concerned about the outcome of their actions. This expression can be used when you or someone else is preoccupied or anxious over something you have no control over.